BioPharma Product Technology Transfer
The main purpose of this project was to upgrade the existing technology in a manufacturing area to improve cycle time and process robustness. Some of the biggest challenges we faced were:
• having to implement our solution during operations
• full gowning while working
• limited shutdown windows
• close cooperation among crafts
To guarantee success, we used the Integrated Project Delivery (IPD) approach that calls for tight collaboration between owner, design firm, construction management firm and the main contractors.
We were appointed as the Electrical & Instrumentation contractor partner for this project. Our duties included: the purchase and installation of new process equipment such as: holding tanks, micro-filtration skids, cryo vessels and scales as well as retrofits of existing equipment such as: UF/DF, CIP, Harvest tanks and ancillary equipment.
They also involved changes of electrical, instrumentation & controls and utilities. Our scope of work included clean rooms as well as mechanical spaces, and the areas impacted were Media Hold, Cell Culture Harvest, Purification and Bulk Fill.
The project also included manufacturing of 40 new control, electrical and pressure monitoring panels at our very own panel manufacturing shop.
Reverse Phase Superskid
Our client requested the fabrication of a Reverse Phase Skid. We were asked to fabricate and install the control panels and install PVC coated conduits and wires for the signals between the control panels, Foundation Fieldbus and DeviceNet instruments. In addition to the 6 main control panels, 16 small control boxes for Foundation Fieldbus and DeviceNet had to be furnished and installed. Our scope of work also included the installation of pneumatic control valves.
New Blending Facility Expansion Project
A major rum manufacturer contacted us to help them with an expansion project for a new blending facility, an existing and a new tank farm and truck unloading facility. We were involved in:
• Panel fabrication
• Installation of DeviceNet
• Instrument procurement
• Electrical installations on explosion areas
Purification Upgrade Project
Client: Leading Biopharma Company in Puerto Rico
Fermentation Upgrade Project
The Fermentation Upgrade Project impacted an existing customer area to accommodate the expansion of an insulin production facility. The scope of work included explosive & corrosive areas and mechanical spaces:
• we installed additional storage tanks
• purchased and installed new process equipment (such as holding tanks)
• performed changes in the electrical system, instrumentation & controls and utilities to support production modifications.
We also provided support for start-up and passivation.